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Mark R Bray Selected Research

human AKT2 protein

1/2003Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells.

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Mark R Bray Research Topics

Disease

16Neoplasms (Cancer)
03/2022 - 12/2002
4Ovarian Neoplasms (Ovarian Cancer)
01/2013 - 01/2003
3Breast Neoplasms (Breast Cancer)
01/2013 - 01/2003
2Aneuploidy (Aneuploid)
03/2022 - 01/2017
2Hypertension (High Blood Pressure)
10/2016 - 02/2011
2Fatigue
10/2016 - 02/2011
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2012 - 09/2003
2Multiple Myeloma
01/2011 - 08/2010
1Liver Neoplasms (Liver Cancer)
03/2022
1Neutropenia
01/2019
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
10/2016
1Constipation
10/2016
1Abdominal Pain (Pain, Abdominal)
10/2016
1Diarrhea
10/2016
1Dysphonia (Spastic Dysphonia)
10/2016
1Dyspnea (Shortness of Breath)
10/2016
1Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
10/2016
1Genomic Instability
11/2015
1Triple Negative Breast Neoplasms
01/2013
1Ovarian Epithelial Carcinoma
01/2013
1Rheumatoid Arthritis
12/2012
1Nausea
02/2011
1Vomiting
02/2011
1Melanoma (Melanoma, Malignant)
01/2011
1Leukemia
01/2011
1Plasmacytoma
08/2010
1Colorectal Neoplasms (Colorectal Cancer)
06/2010
1Carcinoma (Carcinomatosis)
11/2007
1Hodgkin Disease (Hodgkin's Disease)
05/2004
1Neoplasm Metastasis (Metastasis)
01/2003

Drug/Important Bio-Agent (IBA)

9Phosphotransferases (Kinase)IBA
03/2022 - 01/2003
7ENMD 2076IBA
10/2016 - 06/2010
4Pharmaceutical PreparationsIBA
10/2016 - 02/2011
4Aurora KinasesIBA
10/2016 - 08/2010
32- (3- (4- ((2,6- dimethylmorpholino)methyl)styryl)- 1H- indazol- 6- yl)- 5'- methoxyspiro(cyclopropane- 1,3'- indolin)- 2'- oneIBA
03/2022 - 08/2014
3PlatinumIBA
01/2013 - 01/2011
2DNA (Deoxyribonucleic Acid)IBA
03/2022 - 09/2003
2Aurora Kinase AIBA
11/2015 - 06/2010
2Tyrosine (L-Tyrosine)FDA Link
01/2011 - 06/2010
1RNA (Ribonucleic Acid)IBA
01/2019
1Immunoglobulin M (IgM)IBA
01/2019
1CFI-402257IBA
01/2017
1Estrogen ReceptorsIBA
01/2013
1Biomarkers (Surrogate Marker)IBA
01/2013
12-MethoxyestradiolIBA
12/2012
1Estradiol (Delestrogen)FDA LinkGeneric
12/2012
1Antimitotic AgentsIBA
12/2012
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2010
1Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
06/2010
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
06/2010
1EnzymesIBA
11/2007
1Histone Deacetylases (Histone Deacetylase)IBA
04/2005
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
03/2005
1InterleukinsIBA
05/2004
1AutoantibodiesIBA
09/2003
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2003
1WortmanninIBA
01/2003
1TensinsIBA
01/2003
1Proteins (Proteins, Gene)FDA Link
01/2003
1IntegrinsIBA
01/2003
1Complementary DNA (cDNA)IBA
01/2003
1CollagenIBA
01/2003
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2003
1human AKT2 proteinIBA
01/2003
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2003
1Epidermal Growth Factor (EGF)IBA
12/2002
1Immunoglobulin G (IgG)IBA
12/2002

Therapy/Procedure

2Oral Administration
01/2017 - 08/2014
1Therapeutics
11/2015